Winsock Packet Editor (WPE) Pro is a packet sniffing/editing tool.
From my experience using it before on real tibia servers, you can basically send the same or altered packets that have been sent before.
Unless you know how to program into the client/server to check for these packets, and then ensure these exact packets haven't been sent before.. there is no way to stop this program.
Even if you can detect the wrong packets, it only allows players to perform the actions 10x a second.
The amount of activity that wpe pro gives as a footprint is about 4-6x less then a single running bot, and much harder to detect.
The port it uses is the standard game server port 7172, as it simply sends packets that have already been sent before.
I would venture to guess that this program itself is not the cause of your lag.
Sorry for the somber news.